Physical function in patients
Anthony Wales Cancer Trials Unit Dr Anthony Byrne, Cardiff University
Start date: July 2011
Duration: 12 months
Funded amount: £29,955
Regular exercise is important in maintaining our physical strength and independence. In earlier stages of cancer it can improve daily functioning and quality of life. However it is in the advanced stages of cancer that the ability to perform activities of daily living, and remain independent is most threatened.
Before recommending exercise in more advanced illness, it is necessary to have a better understanding of the degree to which cancer-associated weight loss affects physical functioning. One way to do this is to measure changes in muscle strength and balance over time. In order to design effective interventions to address loss of function, it is equally important to understand what would motivate us to exercise in this situation and preferences for the type of exercise. We can then design activities which are relevant and likely to be undertaken in the real world of patients' lives.
This study will measure strength in core muscle groups in 50 patients 3 times over an 8 week period. It will also investigate motivations and preferences for physical activity and exercise in 200 patients using a questionnaire. All patients will have a diagnosis of lung or gastrointestinal cancer. The results of the study will inform future research where the benefits of exercise can be assessed in a large study before becoming part of our clinical care.
Dr Anthony Byrne, Scientific Lead for Palliative Care Research, Wales Cancer Trials Unit, Cardiff University
Dr Robert van Deursen, Director of Research, Dept of Physiotherapy, School of Healthcare Studies, Cardiff University
Dr Karianne Backx, Discipline Director Physiology and Health, Cardiff School of Sport, University of Wales Institute Cardiff
Dr Annmarie Nelson, Marie Curie Senior Research Fellow, Wales Cancer Trials Unit, Cardiff University
Dr David Wasley, Senior Lecturer, Cardiff School of Sport, University of Wales Institute Cardiff
Dr Nichola Gale, Research Assistant, Dept of Physiotherapy, School of Healthcare Studies, Cardiff University
Dr Stephanie Enright, Senior Lecturer, Dept of Physiotherapy, School of Healthcare Studies, Cardiff University
Mr Gareth Griffiths, Scientific Director, Wales Cancer Trials Unit, Cardiff University
Dr Richard Adams, Consultant Clinical Oncologist
Dr Jason Lester, Consultant Clinical Oncologist
Dr Dianne Parry, Consultant Chest Physician
The study is a result of collaboration between the School of Health Sciences, The Marie Curie Research Centre and Wales Cancer Trials Unit at Cardiff University and the Cardiff School of Sport, UWIC. This interdisciplinary research group emerged from the All Wales Rehabilitation Research Network (Wales School of Primary Care Research), and is allied to the Palliative Care Research Group of NISCHR Cancer Registered Research Group and directly links with the UK wide NCRI Palliative Care CSG.