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Cymraeg

Research

Completed PhD student projects

Tenovus Cancer Care has a proud history of supporting generations of cancer researchers. In fact, over the past 50 years we’ve supported over 250 PhD students who have gone on to work on world-class cancer research in labs across the world.

Below are the laboratory research projects that have been completed by Tenovus Cancer Care funded PhD studentships.

To see our current lab projects, click here.

2011, 2010, 2009

 

2013

The role of nucleotide excision repair in providing resistance to the nucleoside analogues Gemcitabine and Cytarabine

Student: Helena Robinson
Supervisor: Dr Edgar Hartsuiker
Location: Bangor University
Cancer Type: All
Start and End Date: June 2013 – Sept 2017

The role of Reactive Oxygen Species (ROS) and glycolytic metabolism in leukaemogenesis

Student: Andrew Robinson
Supervisor: Dr Alex Tonks
Location: Cardiff University
Cancer Type: Leukaemia (Blood)
Start and End Date: Oct 2013 – Dec 2017

The role of STEAP2 in prostate cancer invasion and metastasis

Student: Stephanie Burnell 
Supervisor: 
Professor Shareen Doak
Location: 
Swansea University
Cancer type: 
Prostate
Start and end date: 
Oct 2013 – Sept 2016


Testing the efficacy of iFLIP/TRAIL mediated cytotoxicity in breast tumour tissues ex vivo

Student: Andreia Silva 
Supervisor: Dr Richard Clarkson
Location: Cardiff University
Cancer type: Breast
Start and end date: Oct 2013 – Jan 2017

Treating Metastatic Disease by Manipulation of Regulatory T Cells

Student: Ellyn Hughes 
Supervisor: Professor Awen Gallimore
Location: Cardiff University
Cancer type: All - Metastasis
Start and end date: Oct 2013 – Sept 2016

Molecular and functional characterisation of the nutri-epigenetic effects of chemopreventative polyphenols in intestinal cancer

Student: Stephanie May 
Supervisor: Professor Ros John
Location: Cardiff University
Cancer type: Bowel
Start and end date: Oct 2013 - Sept 2016
Funded by the Jane Hodge Foundation

2011

Human Papillomavirus integration events and cervical disease progression post-vaccination

Student: Rachel Houghton 
Supervisor: Dr Sam Hibbitts
Location: Cardiff University
Cancer type: Cervical
Start and end date: Oct 2011 - March 2015

Human gammadelta T cells for immunotherapy of breast cancer

Student: Hung Chang Chen 
Supervisor: Dr Matthias Eberl
Location: Cardiff University
Cancer type: Breast
Start and end date: Oct 2011 - July 2016

TROP2, a stem cell marker with oncogenic potential in prostate cancer

Student: Tim Wanger 
Supervisor: Dr Vera Knauper
Location: Cardiff University
Cancer type: Prostate
Start and end date: Oct 2011 - Oct 2014

Identifying genes associated with severe toxicities in the treatment of advanced colorectal cancer

Student: Michelle Coffey 
Supervisor: Professor Jeremy Cheadle
Location: Cardiff University
Cancer type: Bowel
Start and end date: Oct 2011 - March 2015

The role of RAGE in the development of Endometrial Cancer

Student: Julia Davies 
Supervisors: Dr Steve Conlan and   Dr Lavinia Margarit
Location: Swansea University
Cancer type: Womb
Start and end date: Oct 2011 - Oct 2015

Characterising the role of Cbx3/Hp1gamma in normal intestinal homeostasis and tumourigenesis

Student: Ka (Chammy) Ian Lio 
Supervisor: Dr Karen Reed
Location: Cardiff University
Cancer type: Bowel
Start and end date: Oct 2011 – Oct 2014

Developing liver and intestinal organ cultures lacking Axin gene function for drug discovery

Student: Annika Offergeld 
Supervisor: Professor Trevor Dale
Location: Cardiff University
Cancer type: Liver and Colon
Start and end date: Oct 2011 – September 2015

Decoding the Genetics of Brain Tumour Development

Student: Karolina-Janina Jaworek 
Supervisor: Dr Claudia Barros
Location: Bangor University
Cancer type: Brain
Start and end date: Oct 2011 – September 2015

2010

Artificially enhanced T-Cells for targeting cancer

 Student: Florian Madura 
Supervisor: Professor Andrew Sewell
Location: Cardiff University
Cancer type: Melanoma (Skin)
Start and end date: Oct 2010 – Jan 2013
This research project was proudly supported by the Tenovus Cancer Care Trust

Deciphering the role of the G-coupled receptor GPR56 in glioblastoma

Student: Lea Bauer 
Supervisor: Dr Vera Knauper
Location: Cardiff University
Cancer type: Brain
Start and end date: Oct 2010 – Sept 2013

2009

Investigating c-FLIP knockdown in vivo as a potential therapy for breast cancer

Student: Luke Piggott 
Supervisor: Dr Richard Clarkson
Location: Cardiff University
Cancer type: Breast
Start and end date: Oct 2009 – Oct 2012

Investigating the immediate and therapeutic effects of MEK inhibition and PI3K inhibition in a genetically defined and clinically relevant autochthonous model of human colorectal cancer.

Student: Meera Raja 
Supervisor: Professor Alan Clarke
Location: Cardiff University
Cancer type: Bowel
Start and end date: Oct 2009 – Sept 2012
This research project was proudly supported by the Jane Hodge Foundation

Structural analysis of the mTOR kinase domain by X-ray crystallography

Student: Rienk Doetjes 
Supervisor: Professor Tony Lai
Location: Cardiff University
Cancer type: All
Start and end date: Oct 2009 – March 2014

Identifying novel alleles that predispose to colorectal cancer

Student: Hannah West 
Supervisor: Professor Jeremy Cheadle
Location: Cardiff University
Cancer type: Bowel
Start and end date: Oct 2009 – Sept 2013
This research project was proudly supported by The Kidani Memorial Trust