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Oct 2019 - Jul 2021

Investigating the Role of Ca2+ Release and Ca2+ Entry in the Development of Asparaginase-Induced Acute Pancreatitis within Pancreatic Acinar and Stellate Cells


David Evans




Dr Oleg Gerasimenko

Cancer Type


Funding Type




Research Type

Cancer Progression and Metastasis


The study that was carried out by the team investigating the effects of potential therapeutics which could aid combat the occurrence of Acute Pancreatitis in patients who are currently undergoing treatment for Acute Lymphoblastic Leukaemia.


The team has been able to identify key therapeutics which showed a significant potentiation of the known effects in combating the development of Acute Pancreatitis.


The results which have been obtained could help future Acute Lymphoblastic Leukaemia patients by preventing the development of Acute Pancreatitis during their vital cancer treatment.

Next Steps

The continuation of this research project is essential with clear steps and targets which are vital in order to test the potential therapeutics and effectiveness of preventing the development of Acute Pancreatitis.

The funding provided by Tenovus Cancer Care was essential in order to conduct our vital research. Without Tenovus Cancer Care it would not have been possible to identify synergistic protective effects that will allow development of potential therapeutics to aid the battle against cancer.

If you or someone you love has been affected by cancer, our free Support Line is there for you. Just call 0808 808 1010